Posts Tagged ‘Nandrolone’

Nandrolone, Testosterone and Anabolic Steroids

Monday, September 29th, 2008

Nandrolone (AKA 19-Nor-Testosterone or 19-Nor-Androstenolone) is an Anabolic Steroid. As the names suggests, it is related to Testosterone, a “male” hormone produced naturally in humans (male AND female) in varying quantities. All Anabolic steroids have “Androgenic” effects, which are the actions we commonly associate with Testosterone; masculinisation, aggression, virilisation, growth, but only up to a point, and with (serious!) reservations. Anabolic steroids also have “Anabolic” effects, those associated with growth of bone, muscle, red blood cells and mobilization of sugar. These are more the effects sought by athletes abusing this range off drugs. Although some Testosterone type anabolics are orally active, they undergo a very heavy Liver process, removing a lot of their action, and also stressing the liver. Serious abusers, or legitimate patients tend to have injections, or to take safer more orally compatible anabolics like Stanazolol (the drug found twice in Ben Johnston’s blood)

Anabolic steroids when used legitimately are used most often to stimulate some sort of growth, so are used in advanced osteoporosis, certain breast cancers, regeneration of red blood cells in kidney patients, puberty disorders, growth disorders, anemia, and to help gonad development (in males). Illegitimate use is focused on increasing muscle mass and strength, but will also increase red blood cell production, therefore blood thickness and oxygen-carrying capacity.

Nandrolone is produced in both males and females as a metabolite (by-product) of Testosterone, and studies have shown it can be elevated to a very detectable level. The studies however did NOT prove the elevated levels would exceed the IOC threshold for a positive test. They barely reached a quarter of this value.

The risks are something the takers ignore, or the suppliers say nothing about. Added to this is the fact that the IOC was able to find Nandrolone in over 14% of muscle-building supplements it tested, all claiming to be “natural”, “safe” or “steroid free” athletes’ health may be at risk simply by taking untested muscle or strength supplements.

The side effects are horrendous and are MORE likely to be serious the younger athletes take Anabolics. They include virilisation in males, early fusion of growing bones (stops growth) in teenagers, growth of breasts in males, androgenisation of females (loss of feminine sexual characteristics), Liver cancers, hepatitis, heart disease, cholesterol elevation, blood sugar elevation, epileptic fits, fluid retention, and ultimately heart-attack and stroke.

In defence athletes often ask why would anyone take Nandrolone when there are better illegal substances for middle-distance or endurance athletes? This is indeed debatable, and MAY suggest the taking has been more inadvertent, but maybe this last possibility is the exact reason they take it. They can suggest a defence saying it must have been in one of the supplements. Nandrolone helps muscle grow, and muscle stores glycogen, so no matter what the sport, if taken with the right type of training, it will improve endurance, strength and oxygen-carrying capacity.

Athletes should be VERY careful about what they take, and coaches more so. Remember health advice sites are rarely overtly commercial, but sites selling Ephedra, weight-loss and performance products are exactly that - commercial! You may receive a contaminated product in the post, but try chasing up the supplier! It’s a case of - if the substance is found in your system then you are guilty regardless.

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Anabolic steroids

Monday, September 29th, 2008

Anabolic steroids are artificial (synthetic) versions of the male hormone testosterone that help build muscle. They also enhance masculine characteristics.

Because they can help the body to form lean muscle, they are sometimes used to treat AIDS wasting and weight loss, and doctors sometimes prescribe them to people experiencing fat loss from the limbs because of lipodystrophy. Testosterone supplements are also used to treat low testosterone levels which can develop in people with HIV due to HIV infection, some other infections, anti-HIV drugs and other medicines.

Anabolic steroids are also widely used by body builders and by many people who weight train at the gym.

Anabolic steroid treatment in people with HIV
The anabolic steroids have been studied as a treatment for AIDS wasting, and have been shown to be safe and effective, helping the formation of lean muscle mass. To be most effective, anabolic steroid treatment should be combined with a programme of resistance training.

Studies have been restricted to men because of concerns about the side-effects of steroid treatment for women.

There have been concerns that the use of anabolic steroids can depress the immune system. This has not been looked at in any great detail. The only study to examine this found that neither CD4 nor CD8 cell count were lowered in HIV-positive men with AIDS wasting treated with anabolic steroids.

Anabolic steroids can increase levels of LDL (bad) cholesterol, so their use should be closely monitored particularly if you are taking a protease inhibitor or have any risk factors for heart disease.

Testosterone replacement therapy in people with HIV
It is estimated that as many as 40% of HIV-positive men who are ill because of HIV have low levels of testosterone (hypgonadism). Low testosterone can result in decreased appetite, depression, poor metabolism of food, and sexual problems, including the inability to obtain and maintain an erection.

A blood test can tell if you have low levels of testosterone and your doctor may prescribe you either a short course of oral testosterone replacement therapy, testosterone patches, or testosterone gel.

Although testosterone is usually considered to be the male sexual hormone, it also occurs naturally in women. Testosterone patches have been examined as a treatment for AIDS wasting in women. It was found that weight and quality of life improved for some of the women, and the development of male characteristics was not reported.

Side-effects from testosterone replacement therapy are rare, but can include the shutting down of natural testosterone production, shrinking of the testicles, hair loss, increased sexual desire, and aggression. In women, male characteristics, such as the deepening of the voice, and facial hair may develop.

Anabolic steroid use for non-medical purposes
Anabolic steroids are often used by people who weight train to improve the effects of training and for aesthetic reasons. They are usually used in four-week cycles, followed by a period off “treatment.”

The use of anabolic steroids in this way is rarely medically supervised, and this may involve considerable health risks.

Health risks of anabolic steroid use
Anabolic steroids, and testosterone, can damage the liver, and severe liver problems including liver fibrosis, cirrhosis and cancer have been seen in long-term users of anabolic steroids. If you are being prescribed them by your doctor, your liver function will be closely monitored.

Acne, male pattern baldness, sexual dysfunction, the shrinking of the testicles, and the shutting down of natural production of testosterone can also be caused by anabolic steroids. Aggression, mood disturbances, stomach pain, an enlarged prostate and water retention can also develop as a consequence of steroid use. Breast enlargement in men, and the development of male characteristics in women have also been observed.

It you are buying steroids on the black market it’s unlikely that you can verify if they are genuine or be certain of their quality. Counterfeit steroids are common and may contain impurities that cause infections or abscesses.

When used in a non-medical context, anabolic steroids are often injected. Sharing needles to inject steroids involves the same health risks as sharing needles to inject recreational drugs, including HIV transmission, and infection with hepatitis C virus and hepatitis B virus.

Legal status of anabolic steroids
Anabolic steroids are a prescription only medicine. Although possession of anabolic steroids is not illegal, selling them is and can involve a fine and a prison sentence.

If you take part in any form of competitive sport, then it’s likely that the use of anabolic steroids will be banned, even if you are taking them for legitimate medical reasons.

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Nandrolone

Wednesday, January 16th, 2008

Retabolil (Nandrolone Decanoate)Deca durabolin is a favorite to thousands of steroid users. In our recent survey, it was revealed that Deca is the most widely used anabolic steroid. It is easy on the liver and promotes good size and strength gains while reducing body fat.

Although nandrolone decanoate is still contained in many generic compounds, almost every athlete connects this substance with Deca-Durabolin. Organon introduced Deca-Durabolin during the early 1960’s as an injectable steroid available in various strengths. Most common are 50 mg/ml and 100 mg/ml. Deca-Durabolin is the most widespread and most commonly used injectable steroid. Deca’s large popularity can be attributed to its numerous possible applications and, for its mostly positive results. The distinct anabolic effect of nandrolone decanoate is mirrorred in the positive nitrogen balance.” Nitrogen, in bonded form. is part of protein. Deca Durabolin causes the muscle cell to store more nitrogen than it releases so that a positive nitrogen balance is achieved. A positive nitrogen balance is synonymous with muscle growth since the muscle cell, in this phase, assimilates (accumulates) a larger amount of protein than usual. The same manufacturer, however, points out on the package insert that a positive nitrogen balance and the protein building effect that accompany it will occur only if enough calories and proteins are supplied. One should know this since, otherwise, satisfying results with Deca Durabolin cannot be obtained.

The highly anabolic effect of Deca durabolin is linked to a moderately androgenic component, so that a good gain in muscle mass and strength is obtained. At the same time, most athletes notice considerable water retention which, no doubt, is not as distinct as that with injectable testosterones but which in high doses can also cause a smooth and watery appearance. Since Deca-Durabolin also stores more water in the connective tissues, it can temporarily ease or even cure existing pain in joints. This is especially good for those athletes who complain about pain in the shoulder, elbow, and knee; they can often enjoy pain-free workouts during treatment while using Deca-Durabolin. Another reason for this is that it blocks the cortisone receptors thus allowing less cortisone to reach the muscle cells and the connective tissue cells. Athletes use Deca, depending on their needs, for muscle buildup and in preparation for a competition. Deca-Durabolin is suitable, even above average, to develop muscle mass since it promotes the protein synthesis and simultaneously leads to water retention. The optimal dose for this purpose lies between 200 and 600 mg/week. Scientific research has shown that best results can be obtained by the intake of 2 mg/pound body weight. Those who take a dose of less than 200 mg/week will usually feel only a very light anabolic effect which, however, increases with a higher dosage. The anabolic and consequent buildup effect of decadurabolin, up to a certain degree, depends on the dosage. In the range of approx. 200 to 600 mg/week, the anabolic effect increases almost proportionately to the dosage increase. If more than 600 mg/week are administered, the relationship of the positive to the negative effects shifts in favor of the latter.In addition, at a dosage level above 600 mg/week, the anabolic effect no longer increases proportionately to the dosage increase, so that 1000 mg/week do not guarantee significantly better results than 600 mg/week.

Most male athletes experience good results by taking 400 mg/week. Steroid novices usually need only 200 mg/week. Deca Durabolin works very well for muscle buildup when combined with Dianabol (D-bol) and Testoviron Depot. The famous Dianabol (D-bol)/Deca stack results in a a fast and strong gain in muscle mass. Most athletes usually take 15-40 mg Dianabol (D-bol)/day and 200-400 mg Deca/week. Even faster results can be achieved with 400 mg Deca/week and 500 mg Sustanon/week. Athletes report an enormous gain in strength and muscle mass when taking 400 mg Deca/week, 500 mg Sustanon/week, and 30 mg Dianabol (D-bol)/day. Deca is a good basic steroid which, for muscle buildup, can be combined with many other steroids. Although Deca is not an optimal steroid when preparing for a competition, many athletes also achieve good results during this phase. Since Deca Durabolin is a long-term anabolic, there is risk that with a higher dosage, the competing athlete will retain too much water. A conversion into estrogen, that means an aromatizing process, is possible with deca durabolin but usually occurs only at a dose of 400 mg/week.

During competitions with doping tests Deca must not be taken since the metabolites in the body can be proven in a urine analysis up to 18 months later. Those who do not fear testing can use Deca as a high-anabolic basic compound in a dosage of 400 mg/week. The androgens contained in 400 mg/week also help to accelerate the body’s regeneration. The risk of potential water retention and aromatizing to estrogen can be successfully prevented by combining the use of Proviron with Nolvadex. A preparatory stack often observed in competing athletes includes 400 mg/week Deca-Durabolin, 50 mg/day Winstrol, 228 mg/week Parabolan, and 25 mg/day Anavar. Although the side effects with Deca-Durabolin are relatively low with dosages of 400 mg/week, androgenic-caused side effects can occur. Most problems manifest themselves in high blood pressure and a prolonged time for blood clotting, which can cause frequent nasal bleeding and prolonged bleeding of cuts, as well as increased production of the sebaceous gland and occasional acne. Some athletes also report headaches and sexual overstimulation. When very high dosages are taken over a prolonged period, spermatogencsis can be inhibited in men, i.e the testes produce less testosterone. The reason is that Deca Durabolin, like almost all steroids, inhibits the release of gonadotropin from the hypophysis.

Women with a dosage of up to 100 mg/week usually experience no major problems with Deca Durabolin. At higher dosages androgenic-caused virilization symptoms can occur, including deep voice (irreversible), increased growth of body hair, acne, increased libido, and possibly clitorishypertrophy. Since most female athletes get on well with Deca-Durabolin a dose of Deca 50 mg+/week is usually combined with Anavar 10 mg+/day. Both compounds, when taken in a low dosage, are only slightly androgenic so that masculinizing side effects only rarely occur. Deca, through its increased protein synthesis, also leads to a net muscle gain and Anavar, based on the increased phosphocreatine synthesis, leads to a measurable strength gain with very low water retention.

Other variations of administration used by female athletes are Deca-Durabolin and Winstrol tablets, as well as Deca-Durabolin and Primobolan’s tablets. Since Deca-Durabolin has no negative effects on the liver it can even be used by persons with liver diseases. Exams have shown that a combined application of Dianabol / Deca-Durabolin increases the liver values which, however, return to normal upon discontinuance of the 17-alpha alkylated Dianabol and continued administration of Deca-Durabolin. Even a treatment period with Deca-Durabolin over several years could not reveal a damage to the liver. For this reason Deca-Durabolin combines well with andriol (240-280 mg/day) since andriol is not broken down through the liver and thus the liver function is not influenced either. Older and more cautious steroid users, in particular, like this combination.

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